| Thermo Fisher Scientific | Franklin | Dec 31, 2026 | 103 | layoff |
| P1 Logistics LLC | Littleton | Oct 24, 2026 | 77 | layoff |
| EMD Serono Research Development Institute, Inc. | Billerica | Oct 16, 2026 | 20 | layoff |
| Thermo Fisher Scientific | Franklin | Oct 16, 2026 | 15 | layoff |
| Blueprint Medicines Corporation (aka Sanofi Company Blueprint) | Cambridge | Oct 9, 2026 | 229 | layoff |
| Community Healthlink, Inc. (aka CHL) | Worcester and Leominster | Oct 9, 2026 | 639 | layoff |
| SMBC Manubank (aka JeniusBank) | Statewide | Oct 9, 2026 | 3 | layoff |
| Noble Equity Holdings LLC, Noble.com, LLC, Noble Supply & Logistics, LLC (f/k/a Noble Sales Co. Inc.), Tactical & Survival Specialties, LLC (f/k/a Tactical & Survival Specialties, Inc.), Federal Resource Supply Company, LLC (f/k/a Federal Resource Supply Company), and K.D. Analytical Consulting, LLC (aka Noble) | Boston | Oct 9, 2026 | 59 | layoff |
| Pure Safety Group, Inc (dba Guardian Fall) | Franklin | Oct 2, 2026 | 5 | layoff |
| Community Healthlink, Inc. (aka CHL) | Worcester and Leominster | Sep 16, 2026 | 231 | layoff |
| Community Healthlink, Inc. (aka CHL) | Worcester and Leominster | Sep 16, 2026 | 234 | layoff |
| Community Healthlink, Inc. (aka CHL) | Worcester and Leominster | Sep 16, 2026 | 236 | layoff |
| National Express Transit Corp. (dba Kiessling of Attleboro) | Taunton and Wareham | Sep 15, 2026 | 162 | layoff |
| EMD Serono Research Development Institute, Inc. | Billerica | Sep 4, 2026 | 70 | layoff |
| Peabody Opco, LLC (f/k/a Christianbook, LLC) and Peabody Fulfillment, LLC (f/k/a Christianbook Fulfillment, LLC) (aka Christianbook Entities) | Peabody | Aug 31, 2026 | 125 | layoff |
| Joymark, Inc. (dba G2O Spa + Salon) | Boston | Aug 31, 2026 | 55 | layoff |
| Labour� College of Healthcare, Inc. | Milton | Aug 30, 2026 | 65 | layoff |
| The Coca-Cola Company | Northampton | Aug 15, 2026 | 175 | layoff |
| Postal Center International, Inc. (aka PCI) | Franklin | Aug 13, 2026 | 112 | layoff |
| SDH Education East, LLC (aka Sodexo) | Waltham | Aug 11, 2026 | 173 | layoff |
| SMBC Manubank (dba JeniusBank) | Statewide | Aug 3, 2026 | 2 | layoff |
| Chase Corporation | Oxford | Aug 1, 2026 | 72 | layoff |
| Jabil Inc. (aka Jabil - Clinton JHC) | Clinton | Aug 1, 2026 | 103 | layoff |
| Community Healthlink, Inc. (aka CHL) | Leominster | Jul 31, 2026 | 127 | layoff |
| Aramark Campus, LLC (dba Aramark) | Lowell | Jul 14, 2026 | 54 | layoff |
| Dover Saddlery, Inc. | Littleton | Jul 7, 2026 | 112 | layoff |
| Peabody Opco, LLC (f/k/a Christianbook, LLC) and Peabody Fulfillment, LLC (f/k/a Christianbook Fulfillment, LLC) (aka Christianbook Entities) | Peabody | Jul 6, 2026 | 50 | layoff |
| Compass Group USA, Inc. | Boston | Jul 1, 2026 | 83 | layoff |
| Takeda Pharmaceuticals USA, Inc. (dba Takeda) | Cambridge | Jul 1, 2026 | 247 | layoff |
| Innovative Care Partners, LLC (aka ICP) | Northampton | Jun 30, 2026 | 70 | layoff |
| Community Healthlink, Inc. (aka CHL) | Leominster | Jun 30, 2026 | 78 | layoff |
| Community Counseling of Bristol County (aka CCBC) | Attleboro | Jun 30, 2026 | 52 | layoff |
| Managed Services-IDS (dba Cardinal Health) | Tewksbury | Jun 30, 2026 | 58 | layoff |
| Community Healthlink, Inc. (aka CHL) | Leominster | Jun 30, 2026 | 84 | layoff |
| Hampshire College | Amherst | Jun 16, 2026 | 199 | layoff |
| KAC Logistics | East Taunton | Jun 16, 2026 | 40 | layoff |
| South Shore Elder Services | Braintree | Jun 1, 2026 | 131 | layoff |
| Revvity, Inc. | Boston | Jun 1, 2026 | 29 | layoff |
| South Shore Elder Services | Braintree | Jun 1, 2026 | 52 | layoff |
| Walmart | Worcester | May 29, 2026 | 90 | layoff |
| Clover Fast Food, Inc. (Clover) | Cambridge | May 29, 2026 | 182 | layoff |
| Compass Group USA, Inc. (dba Chartwells) | Boston | May 27, 2026 | 76 | layoff |
| MCAT, LLC (dba Harborview Treatment) | Cohasset | May 20, 2026 | 66 | layoff |
| WestRock Services, LLC (aka WestRock and Smurfit Westrock) | Wakefield | May 18, 2026 | 24 | layoff |
| WestRock Services, LLC (aka WestRock and Smurfit Westrock) | Wakefield | May 18, 2026 | 91 | layoff |
| Garlock Flexibles | Gardner | Apr 30, 2026 | 91 | layoff |
| Charles River Laboratories | Wilmington | Apr 24, 2026 | 71 | layoff |
| Charles River Laboratories | Wilmington | Apr 24, 2026 | 71 | layoff |
| *Updated* Charles River Laboratories | Wilmington | Apr 24, 2026 | 71 | layoff |
| Legends Global (dba Legends Attractions, LLC and Legends Music, LLC) | Boston | Apr 22, 2026 | 41 | layoff |
| Boston Electrometallurgical Corporation (dba Boston Metal) | Woburn | Apr 21, 2026 | 71 | layoff |
| Goulet Trucking, Inc. | South Deerfield | Apr 18, 2026 | 144 | layoff |
| Aloha Logistics llc | Taunton | Apr 17, 2026 | 10 | layoff |
| Replimune, Inc. | Woburn | Apr 17, 2026 | 81 | layoff |
| Replimune, Inc. | Framingham | Apr 17, 2026 | 80 | layoff |
| Replimune, Inc. | Woburn | Apr 13, 2026 | 63 | layoff |
| AE Regional Distribution Co., LLC (formerly known as Quiet Logistics, Inc.) | Devens | Apr 12, 2026 | 103 | layoff |
| Saks & Company LLC (dba Neiman Marcus) | Boston | Apr 11, 2026 | 73 | layoff |
| Smithfield Packaged Meats Corp. | Springfield | Apr 10, 2026 | 190 | layoff |
| Zipcar, Inc. (dba Zipcar) | Boston | Apr 1, 2026 | 65 | layoff |
| Panera, LLC (dba Panera) | Franklin | Mar 25, 2026 | 92 | layoff |
| Medford CPL, Inc. | Medford | Mar 17, 2026 | 63 | layoff |
| CRRC MA | Springfield | Mar 16, 2026 | 161 | layoff |
| Boston Electrometallurgical Corporation (dba Boston Metal) | Woburn | Mar 14, 2026 | 71 | layoff |
| SMBC Manubank (dba JeniusBank) | N/A | Mar 10, 2026 | 161 | layoff |
| Curia Global, Inc. | Burlington | Mar 10, 2026 | 81 | layoff |
| SMBC Manubank (dba JeniusBank) | Statewide | Mar 10, 2026 | 161 | layoff |
| Labcorp Early Development Laboratories, Inc. | Bedford | Mar 9, 2026 | 94 | layoff |
| Labcorp Early Development Laboratories, Inc., and Laboratory Corporation of America Holding (dba Labcorp) | Bedford | Mar 9, 2026 | 94 | layoff |
| Tessera Therapeutics, Inc. | Somerville | Mar 8, 2026 | 82 | layoff |
| Nordstrom | N/A | Mar 1, 2026 | 2 | layoff |
| Nordstrom | Statewide | Mar 1, 2026 | 2 | layoff |
| Smyth Companies, LLC | Wilmington | Mar 1, 2026 | 69 | layoff |
| Eastern Bank | Brockton | Feb 21, 2026 | 75 | layoff |
| SynQor, Inc. | Boxborough | Feb 1, 2026 | 250 | layoff |
| Dental Benefit Management, Inc. (dba BeneCare Dental Plans) | Worcester | Jan 31, 2026 | 50 | layoff |
| Rebel Restaurants, Inc. (dba Tony C's and Temazcal) | Boston | Jan 31, 2026 | 84 | layoff |
| ImmunityBio, Inc. | Woburn | Jan 30, 2026 | 1 | layoff |
| Takeda Pharmaceuticals America, Inc. (dba Takeda) | Cambridge | Jan 14, 2026 | 3 | layoff |
| Charles River Laboratories | Wilmington | Jan 6, 2026 | 71 | layoff |
| Charles River Laboratories, Inc. | Wilmington | Jan 6, 2026 | 68 | layoff |
| *Updated* Charles River Laboratories | Wilmington | Jan 6, 2026 | 71 | layoff |
| TJX Companies, Inc. | Boston | Jan 5, 2026 | 117 | layoff |
| Revvity, Inc. | Lawrence | Jan 1, 2026 | 51 | layoff |
| Takeda Development Center Americas, Inc. | Cambridge | Jan 1, 2026 | 137 | layoff |
| Airborn, a Molex Company | Taunton | Dec 31, 2025 | 86 | layoff |
| Empire Hospitality LLC (dba Westford Regency Inn & Conference Center) | Westford | Dec 19, 2025 | 62 | layoff |
| The Fresh Market | Framingham | Dec 14, 2025 | 50 | layoff |
| Revvity, Inc. | Lawrence | Dec 9, 2025 | 52 | layoff |
| *Updated* Revvity, Inc. | Lawrence | Dec 9, 2025 | 52 | layoff |
| Piedmont Airlines, Inc. | Boston | Nov 18, 2025 | 61 | layoff |
| AlerisLife, Inc. | Newton | Nov 3, 2025 | 179 | layoff |
| AlerisLife, Inc. | Newton | Nov 3, 2025 | 179 | layoff |
| NGP Management, LLC | Haverhill | Nov 3, 2025 | 74 | layoff |
| *Updated* AlerisLife, Inc. | Newton | Nov 3, 2025 | 179 | layoff |
| Revvity, Inc. | Boston | Nov 1, 2025 | 76 | layoff |
| Revvity, Inc. | Boston | Nov 1, 2025 | 74 | layoff |
| *Updated* Revvity, Inc. | Boston | Nov 1, 2025 | 76 | layoff |
| Kovalus Separation Solutions, LLC | Wilmington | Oct 15, 2025 | 80 | layoff |
| *Updated* Kovalus Separation Solutions, LLC | Wilmington | Oct 15, 2025 | 80 | layoff |
| GSK plc. | Cambridge | Oct 4, 2025 | 150 | layoff |
| Cold Chain Technologies, LLC | Franklin | Oct 1, 2025 | 82 | layoff |
| SDH Services East, LLC (dba-Sodexo) | Brockton | Sep 30, 2025 | 64 | layoff |
| Ayr Wellness Massachusetts - M3 | Milford | Sep 29, 2025 | 157 | layoff |
| Hannaford Bros. Co., LLC | Marlborough | Sep 13, 2025 | 160 | layoff |
| Azurity Pharmaceuticals, Inc. | Wilmington | Sep 12, 2025 | 75 | layoff |
| Tuscan Brands Kitchen | Burlington | Aug 4, 2025 | 38 | layoff |
| Sarepta Therapeutics, Inc. | Cambridge | Jul 18, 2025 | 493 | layoff |
| S&C Corp | Bridgewater | Jun 15, 2025 | 63 | layoff |